Quick Summary for B2B Buyers

• Product: 2-Bromopyridine-5-carbaldehyde
• CAS number: 149806-06-4
• Approximate molecular formula: C₆H₄BrNO
• Approximate molecular weight: 186.01 g/mol
• Main role: A bifunctional heteroaromatic intermediate for synthesis and research
• Best purchasing practice: Match the material grade and documentation to the intended reaction and scale

The most important buying decision is not simply finding the lowest quoted price. I evaluate whether the material has the required identity, purity, analytical support, packaging, and delivery plan for the buyer’s intended use. When project information is limited, I recommend requesting a current specification sheet, SDS, certificate of analysis, and representative sample before approving a larger quantity.

What Is 2-Bromopyridine-5-carbaldehyde?

2-Bromopyridine-5-carbaldehyde is a brominated pyridine aldehyde used as a synthetic building block. The pyridine nitrogen provides a basic and coordinating heteroatom, while the aldehyde group can participate in condensation and other carbonyl-related transformations. The aryl bromide can also serve as a handle for cross-coupling or other substitution chemistry, subject to the reaction design and conditions selected by the chemist.

Core Chemical Features

The combination of these functional groups makes the molecule useful when a synthesis requires controlled elaboration at more than one position. The aldehyde may be used in reactions such as imine formation, reductive amination, or carbon–carbon bond-forming sequences, while the bromine may be retained for later-stage diversification. Actual reactivity depends on the substrate, catalyst, solvent, temperature, and work-up procedure, so I treat these reactions as application possibilities rather than guaranteed outcomes.

Because aldehydes can be sensitive to storage conditions and handling, I advise buyers to review the supplier’s storage guidance and confirm the appearance and assay of each received batch. A buyer should not infer stability, shelf life, or transportation classification without checking the current SDS and batch documents. Maison Chemical can organize product information for technical and procurement review before shipment.

Typical Uses and Application Scenarios

Pharmaceutical and Medicinal Chemistry

In pharmaceutical intermediate development, 2-Bromopyridine-5-carbaldehyde can support the preparation of substituted pyridines and exploratory compound libraries. Its two reactive handles allow researchers to vary side chains, ring substituents, and heterocyclic connections during structure–activity relationship studies. I position it as a research and synthetic intermediate rather than as an active pharmaceutical ingredient.

Custom Synthesis and Process Development

Custom synthesis teams may select this building block when they need a defined bromopyridine aldehyde for route screening or intermediate preparation. It can be evaluated in laboratory-scale reactions before a process is transferred to larger equipment. For scale-up, I recommend confirming impurity profiles, isolation behavior, reaction conversion, and downstream purification requirements rather than relying only on a catalog description.

Academic and Industrial Research

Research organizations may use the compound for heterocyclic synthesis, catalyst studies, reaction development, and preparation of reference intermediates. The exact application should determine the required grade and quantity. A small research package may be suitable for feasibility work, while a development project normally requires stronger batch consistency and more complete documentation.

Product Specifications Buyers Should Review

I recommend using a written specification rather than accepting a verbal description of quality. The following data points are useful starting points, but the buyer should confirm the values on the current product specification and certificate of analysis supplied for the relevant batch.

The example purity value of 98% is a purchasing threshold that a buyer may specify; it is not a claim that every batch has this result. I confirm the actual assay and test method through the applicable certificate of analysis. Depending on the project, buyers may also request water content, residual solvents, elemental impurities, heavy metals, and storage or retest information.

How to Select the Right Supply Option

Step 1: Define the Intended Use

First, I ask whether the material is intended for reaction screening, medicinal chemistry, process development, or commercial intermediate production. This determines the appropriate quantity, documentation level, packaging format, and acceptance criteria. It also helps prevent over-specifying an expensive grade for a low-risk research experiment or under-specifying material for a regulated development program.

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Step 2: Set Quality and Documentation Requirements

The buyer should identify the minimum assay, acceptable impurity profile, analytical methods, and document package before comparing quotations. A current SDS is important for safe handling, while a batch-specific certificate of analysis supports incoming quality control. If the buyer requires a particular test method, I recommend stating it during the inquiry rather than after production.

Step 3: Confirm Quantity, Packaging, and Delivery

Quantity should be connected to the project schedule and expected consumption. I normally distinguish between sample quantities, laboratory quantities, development quantities, and repeat commercial orders because each can involve different packing and lead-time arrangements. Buyers should also confirm whether the product is shipped in a moisture-protective inner container and whether the outer packaging meets the agreed transport requirements.

Step 4: Review Commercial Terms

Price, minimum order quantity, payment terms, lead time, and shipping terms all affect the actual procurement cost. I recommend comparing total delivered cost and supply risk rather than unit price alone. For a first order, a representative sample or small qualification batch can reduce the risk of discovering an unsuitable impurity profile after a larger purchase.

Common Buyer Mistakes

One frequent mistake is purchasing by chemical name alone without checking the CAS number and structure. Similar pyridine aldehydes can have different substitution positions, molecular weights, and reaction behavior. I also advise buyers to avoid treating a generic product page as a substitute for batch-specific analytical documentation.

Another mistake is failing to define the required purity method. HPLC area percentage, GC area percentage, assay by another method, and isolated yield are not interchangeable measurements. Buyers should specify the acceptance method and ask the supplier to confirm whether the reported result is comparable to their internal quality procedure.

Finally, buyers sometimes postpone logistics discussions until after technical approval. Packaging, temperature guidance, export documents, and lead time can influence whether a material arrives in time for a scheduled campaign. Addressing these points in the initial inquiry makes the sourcing process more predictable.

How Maison Chemical Supports Procurement

At Maison Chemical, I support B2B buyers by organizing product, quality, and commercial information around the intended application. I can discuss the required quantity, target specification, analytical documents, packaging expectations, and delivery destination before preparing a quotation. This approach helps technical and purchasing teams review the same requirements.

For pharmaceutical intermediate projects, I recommend a staged evaluation: confirm the identity and specification, review analytical evidence, assess a sample where appropriate, and then discuss repeat supply. I do not present unsupported certifications, customer claims, or guaranteed performance. Instead, I provide the available documentation and encourage the buyer to complete its own qualification procedures.

Information to Include in an Inquiry

1. Required product name and CAS number: 2-Bromopyridine-5-carbaldehyde, CAS 149806-06-4.
2. Estimated quantity and whether the order is for sample, research, development, or repeat supply.
3. Target assay, impurity limits, analytical methods, and required documents.
4. Preferred packaging, destination, delivery schedule, and shipping terms.
5. Any storage, sample approval, or quality agreement requirements.

With these details, I can provide a more relevant response and identify any information that still needs confirmation. Buyers who are comparing multiple suppliers can use the same inquiry format to evaluate offers consistently.

Conclusion and Next Steps

2-Bromopyridine-5-carbaldehyde CAS 149806-06-4 is a useful bifunctional pyridine intermediate for synthetic research, medicinal chemistry, and custom development work. Its bromine and aldehyde groups offer complementary opportunities for molecular diversification, while its approximate molecular weight of 186.01 g/mol supports straightforward stoichiometric planning. The right supply decision depends on verified identity, batch quality, documentation, packaging, and delivery requirements.

I recommend starting with a clear technical specification and requesting the current SDS, certificate of analysis, available analytical data, quotation, MOQ, and lead-time information. Maison Chemical can support this evaluation as a manufacturer, supplier, and export partner for B2B chemical procurement. Send your target quantity, required specification, destination, and project timeline so I can prepare a practical supply proposal for your review.